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By contrast with a plenty of our
2023-08-15

By SMER 3 australia with a plenty of our understanding on arginine metabolism in animals and higher plants, very little thus far is known on the specific function of arginase that acts as a key control point for keeping arginine balance in edible mushrooms and neither for its physiological role in
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br STAR Methods br Acknowledgments We thank Simcere
2023-08-15

STAR★Methods Acknowledgments We thank Simcere Pharmaceuticals, Nanjing, China, for providing a rabbit anti-VEGF neutralizing monoclonal antibody. We thank Dr. Schlisio in the Ludwig Institute for Cancer Research, Karolinska Institute, for assistance with hypoxia assay. Y.C.’s laboratory is sup
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lamotrigine mg br Introduction Increased renin angiotensin s
2023-08-15

Introduction Increased renin-angiotensin system (RAS) activity and inflammation in cardiovascular-related regions of the central nervous system contribute to the overactivity of neurohumoral systems that promote volume retention, cardiac remodeling and serious cardiac arrhythmias in systolic hear
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The most common adverse effects were ARIA which occurred at
2023-08-15

The most common adverse effects were ARIA, which occurred at higher levels than in any previous anti-Aβ mAb study. ARIA-E was observed at some point during the trial in no participants in the placebo group compared with 1 (3%), 2 (6%), 11 (37%), and 13 (41%) participants receiving 1, 3, 6, and 10 mg
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In addition we aimed to
2023-08-15

In addition, we aimed to examine the possible role of adiponectin in modulating changes in IR. It was observed that there was a simultaneous decline in expression of IR and AdipoR1 proteins in the ovary of PCOS-mice as compared to the control ovary. Further, a strong correlation was found between ch
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NLX a k a F or
2023-08-15

NLX-112 (a.k.a. F13640 or befiradol), exhibits nanomolar affinity at 5-HT1A receptors, and, in angiotensin receptor blocker to the 5-HT1A receptor agonists listed above, it presents exceptional selectivity and high efficacy at these receptors (Colpaert et al., 2002, Newman-Tancredi et al., 2017). A
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br Acknowledgments and Disclosures br Introduction In mammal
2023-08-15

Acknowledgments and Disclosures Introduction In mammals, ejaculated sperm requires a finite period of residence in the female reproductive tract to become competent for fertilization (Visconti et al., 1995a, Visconti et al., 1995b). Once oocytes are matured, it is important for these cells to
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Numerous studies have shown that
2023-08-15

Numerous studies have shown that ω-3 PUFA incorporation into the lipid raft can affect the distribution and function of protein in the lipid raft by altering raft composition [25], [26], [27]. For example, DHA treatment excluded phospholipase D (PLD) from lipid raft toward non-lipid raft, resulting
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br Expression of ADK in the normal
2023-08-15

Expression of ADK in the normal brain In adult brain, ADK is primarily expressed in astrocytes. Immunocytochemical analysis of adult rat and mouse cytochalasin d revealed predominant astrocytic expression throughout the hippocampus and cortex. Two isoforms of ADK have been identified in mammals,
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Introduction Adenosine kinase ADK ATP adenosine phosphotrans
2023-08-15

Introduction Adenosine kinase (ADK; ATP: adenosine 5′-phosphotransferase, EC 2.7.1.20), is isolated from yeast cells by Kornberg for the first time in 1951 [1]. ADK belongs to the ribokinase protein family and is one of the most abundant nucleoside kinases in mammalian tissues [2,3]. As the first i
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The first result of this paper
2023-08-15

The first result of this paper is parallel to the positivity result given in [16]: Here the definition of approximate ACHE metric is the same as in [18]. See Definition 1 for details. The second result of this paper is parallel to the Sulforaphane extension formulae given in [2]. In particular, w
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br Role of LPA in
2023-08-15

Role of LPA in tumor angiogenesis and skeletal metastasis The angiogenesis switch is essential for tumor expansion and escape of tumor mecamylamine receptor from the primary site and forming distant metastases. Evidence for the role of LPA2 and LPA3 in the mobility of endothelial cells and the fo
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Caspase-1, human recombinant proteinase br Acknowledgements
2023-08-15

Acknowledgements We thank Dr. Stefan Schulte-Merker and his group members at the Hubrecht Institute (Utrecht, the Netherlands) for their invaluable support of the zebrafish studies. Our work is supported by grants from the Dutch Cancer Society (KWF) and the Netherlands Organisation for Scientific
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br Introduction Rhamdia quelen jundi Silurifomes Heptapterid
2023-08-14

Introduction Rhamdia quelen (jundiá, Silurifomes, Heptapteridae) is a neotropical catfish widely distributed in Central and South America (Silfvergrip, 1996). This species shows high potential for the aquaculture industry, due to an elevated growth rate, good carcass yield, and easy reproduction
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Based on the results of studies done to
2023-08-14

Based on the results of studies done to-date, there are three characteristics that make a letrozole-based protocol attractive for use in cattle: 1) it is steroid-free, 2) it is cost-effective and requires a shorter time and fewer animal handlings than conventional methods (Table 1), and 3) it may ha
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